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Title: Masculinization Of Genetic Females Of The Common Carp (Cyprinus Carpio L.) By Dietary Administration Of An Aromatase Inhibitor
Authors: Tzchori, Itai
Zak, Tatyana
Sachs, Ofer
Keywords: aromatase inhibitor, common carp, methyltestosterone, sex determination, sex inversion
LC Subject Headings: Fish culture--Israel--Periodicals.
Fish culture--Periodicals.
Issue Date: 2004
Publisher: Israeli Journal of Aquaculture - BAMIGDEH
Citation: Tzchori, I., Zak, T., & Sachs, O. (2004). Masculinization Of Genetic Females Of The Common Carp (Cyprinus Carpio L.) By Dietary Administration Of An Aromatase Inhibitor . The Israeli Journal of Aquaculture - Bamidgeh, 56(4), 239-246.
Series/Report no.: The Israeli Journal of Aquaculture - Bamidgeh
Abstract: In the present study, we demonstrated the ability of Fadrozole, an aromatase inhibitor, to induce sex inversion of genetically female common carp fry during the critical sex differentiation period. Thirty-day-old female fingerlings with a mean initial weight of 4.0 g (experiment I) and 3.5 g (experiment II) were fed a diet containing Fadrozole for 36 or 50 days, respectively. Not a single male was found in the control groups of both experiments. In experiment I, Fadrozole at 200 mg/kg feed resulted in 58.6% males, while fish receiving 17α-methyltestosterone at 50 or 100 mg/kg feed resulted in only 5-10% males. In experiment II, the efficiency of Fadrozole was dose- dependent; the lower dose of 100 mg/kg caused masculinization in 86% of the treated fry while the higher doses of 200 and 400 mg/kg feed increased the percentage of males to 97%. These results confirm the importance of aromatization during the labile period in common carp since low aromatase activity during this period, regardless of genotype, resulted in masculinization.
Pages/Duration: 8 pages
ISSN: 0792-156X
Appears in Collections:IJA Volume 56, Issue 4, 2004

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