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Title: Effects of Dietary Astaxanthin on Innate Immunity and Disease Resistance against Edwardsiella tarda in Olive Flounder Paralichthys olivaceus 
Author: Kim S.; Song J.; Kim K.; Lee K.
Date: 2012
Publisher: Israeli Journal of Aquaculture - BAMIGDEH
Abstract: We report on the non-specific immune responses and disease resistance against Edwardsiella tarda in olive flounder fed diets supplemented by astaxanthin. Four experimental diets were formulated to be isonitrogenous (45% crude protein) and isocaloric (17.1 MJ/kg, dry matter). Astaxanthin was added to the diets at 0 (control), 1%, 2%, and 3%. Three replicate fish groups (30 fish/tank) were fed one of the experimental diets for 15 days. After 15 days, 30 healthy fish per dietary treatment were selected and injected with 1 ml E. tarda suspension to evaluate the disease resistance of the fish. Dietary supplementation of astaxanthin resulted in significantly higher non-specific immune responses than in fish fed the control diet. Cumulative mortality in the challenge test with E. tarda was significantly lower in fish fed the astaxanthin-supplemented diets than in fish fed the control diet. Results indicate that dietary supplementation of astaxanthin can enhance non-specific immune responses and disease resistance of olive flounder against E. tarda, and that a relatively short feeding period of astaxanthin can improve immunity in fish.
Series/Report No.: The Israeli Journal of Aquaculture - Bamidgeh
Pages/Duration: 6 pages
ISSN: 0792-156X
Identifier: IJA_64.2012.740
URI: http://hdl.handle.net/10524/23182
Keywords: Dietary, Astaxanthin, Immunity, Disease, Resistance, Edwardsiella tarda, Paralichthys olivaceus
LC Subject Headings: Fish culture--Israel--Periodicals.
Fish culture--Periodicals.
Aquaculture--Israel--Periodicals.
Aquaculture--Periodicals.

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