Please use this identifier to cite or link to this item:

Catastrophic antiphospholipid syndrome; a "CATASTROPHIC" case of systemic lupus erythematosus.

File SizeFormat 
2004-12p362-364.pdf390.35 kBAdobe PDFView/Open

Item Summary

Title: Catastrophic antiphospholipid syndrome; a "CATASTROPHIC" case of systemic lupus erythematosus.
Authors: Roberts, Jefferson R
Finger, David R
Issue Date: Dec 2004
Abstract: Less than 1% of patients with the antiphospholipid antibody syndrome (APS) can develop multiple, simultaneous organ-system thromboembolic disease, which is referred to as the catastrophic antiphospholipid antibody syndrome (CAPS). Roughly one-half of these patients have systemic lupus erythematosus (SLE). Factors known to precipitate CAPS include infection, surgery, trauma, neoplasia, anticoagulation withdrawal, obstetric complications, and SLE flares. Optimal treatment includes anticoagulation and high-dose corticosteroids, although IVIG and plasma exchange may also have a role. The overall mortality of CAPS is roughly 50%, but prompt clinical recognition of this rare but devastating syndrome may lead to improved outcomes.
ISSN: 0017-8594
Appears in Collections:Hawaii Medical Journal Articles For 2004

Items in eVols are protected by copyright, with all rights reserved, unless otherwise indicated.