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Gradual loss of IgG antibodies against GB virus C/hepatitis G virus in a patient with AIDS.
|Title:||Gradual loss of IgG antibodies against GB virus C/hepatitis G virus in a patient with AIDS.|
|Authors:||Nerurkar, V R|
Chua, P K
Shikuma, Cecilia M.
Dashwood, W M
Milne, C I
show 4 moreWoodward, C L
Peterson, J E
|Issue Date:||Dec 1998|
|Abstract:||GB virus C/hepatitis G virus (GBV-C/HGV) is a positive-sense, single-stranded RNA virus belonging to the family Flaviviridae and is distantly related to hepatitis C virus (HCV). GBV-C/HGV can be transmitted by the parenteral and the sexual route. Among individuals infected with human immunodeficiency virus type 1 (HIV-1) by the sexual route, we and others have demonstrated a high prevalence of GBV-C/HGV infection. Recently, Woolley and colleagues reported that AIDS patients co-infected with GBV-C/HGV had a significantly lower mean CD4 cell count than AIDS patients without GBV-C/HGV infection, suggesting that GBV-C/HGV antibody may be lost with progression to AIDS. To our knowledge no data are available on the loss of antibody against GBV-C/HGV in AIDS patients. We now report on an HIV-infected patient who exhibited gradual loss of IgG antibodies against GBV-C/HGV, as well as HCV, with progression of HIV disease.|
|Sponsor:||G12RR/AI-03061/RR/NCRR NIH HHS/United States|
|Appears in Collections:||Hawaii Medical Journal Articles For 1998|
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