Evaluation of human exposure to the heptachlor epoxide contamination of milk in Hawaii.

dc.contributor.authorBaker, D B
dc.contributor.authorLoo, S
dc.contributor.authorBarker, J
dc.date.accessioned2019-07-02T16:18:27Z
dc.date.available2019-07-02T16:18:27Z
dc.date.issued1991-03
dc.description.abstractThe commercial milk supply on Oahu was contaminated by heptachlor epoxide for as long as 15 months during 1981-82 at levels possibly as high as 1.2 ug/g, fat basis. Following the contamination, several investigators attempted to evaluate potential adverse health outcomes, especially among infants and young children. However, results of the initial investigations are inconclusive due to lack of reliable measures of heptachlor exposure, use of non-random sampling techniques, and lack of definitive health outcomes attributable to heptachlor epoxide. The design of a current study to assess the body concentrations of heptachlor epoxide and related pesticides in Hawaii is presented. The study is designed (1) to relate these concentrations to prior exposure via the milk contamination, and (2) to assess the reliability of breast milk and serum pesticide concentrations as objective biological markers of body burden. No attempt is made to relate these data to health outcomes; instead, the findings may provide the foundation for future health studies or surveillance of environmental exposure to pesticides in Hawaii.
dc.identifier.issn0017-8594
dc.identifier.pubmed2061027
dc.identifier.urihttp://hdl.handle.net/10524/62659
dc.language.isoeng
dc.subject.meshAnimals
dc.subject.meshCattle
dc.subject.meshFood Contamination/analysis
dc.subject.meshHawaii
dc.subject.meshHeptachlor Epoxide/adverse effects
dc.subject.meshMaximum Allowable Concentration
dc.subject.meshMilk/chemistry
dc.subject.meshRisk Factors
dc.titleEvaluation of human exposure to the heptachlor epoxide contamination of milk in Hawaii.
dc.typeJournal Article
dc.typeResearch Support, Non-U.S. Gov't
dc.typeReview
dc.type.dcmiText
prism.number3
prism.pagerange108-12, 118
prism.publicationnameHawaii medical journal
prism.volume50

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