Immunogenicity Of Aeromonas Salmonicida A-Protein In Goldfish (Carassius Auratus L.)
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2001
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Israeli Journal of Aquaculture - BAMIGDEH
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Abstract
Antigenicity of the surface A-layer protein of an atypical Aeromonas salmonicida strain was tested in goldfish following immunization with various A-protein (AP) antigenic preparations (soluble form, alum-precipitated, conjugated with polyacrolein nanoparticles, or bacterin). ELISA revealed innate specific anti-AP antibody activity in all fish on day 0, while no significant antibody enhancement was seen on days 21 or 42 following the primary immunization. A second stimulation with soluble AP resulted in a clear response in groups primed with bacterin and alum-precipitated AP but no response in those primed with soluble AP or AP-nanoparticles conjugate. The implication of these results for vaccine design is discussed.
Description
Keywords
Aeromonas salmonicida, A-layer protein immunogenicity, goldfish, Fish culture--Israel--Periodicals., Fish culture--Periodicals., Aquaculture--Israel--Periodicals., Aquaculture--Periodicals.
Citation
Sinyakov, M., Dror, M., Margel, S., & Avtalion, R.R. (2001). Immunogenicity Of Aeromonas Salmonicida A-Protein In Goldfish (Carassius Auratus L.). The Israeli Journal of Aquaculture - Bamidgeh, 53(3 - 4), 110-114.
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5 pages
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