Effects of dietary oxidized fish oil on the growth performance, intestinal health, and antioxidant capacity of zebrafish
Files
Date
2023
Contributor
Advisor
Department
Instructor
Depositor
Speaker
Researcher
Consultant
Interviewer
Narrator
Transcriber
Annotator
Journal Title
Journal ISSN
Volume Title
Publisher
Volume
75
Number/Issue
Starting Page
Ending Page
Alternative Title
Abstract
This study aimed to investigate the effects of oxidized fish oil (OFO) on growth performance, intestinal health, and antioxidant function and to determine the minimum concentration of oxidized fish oil to cause irreversible damage to the intestinal tissue structure of zebrafish. A 30-day feeding trial on zebrafish (average weight 0.054 g) was conducted in triplicate groups of fish fed four test diets containing different concentrations of OFO: 0% OFO (OFF, blank control), 2% OFO (OF1), 4% OFO (OF2), and 6% OFO (OF3). The body weight gain (WG), specific growth rates (SGR), feed conversion ratio (FCR), survival rate (SR), and antioxidant function {glutathione peroxidase (GSH-PX), total superoxide dismutase (T-SOD), catalase (CAT), and malondialdehyde (MDA)} were recorded. The intestinal structure was observed at the end of the trial. After the 14-day experimental period, Final body weight (FBW), WG, and SGR decreased significantly with the increase in the concentration of feed OFO (P < 0.05), while FCR showed a downward trend. The activity of T-SOD decreased significantly, the activities of GSH-PX and CAT, and the MDA content increased significantly with the increase in the concentration of feed OFO (P < 0.05). The intestinal morphological damage score showed an upward trend with the increase in the concentration of OFO, and it was significantly higher in group OF2 and OF3 than in group OF1 (P < 0.05). After the 28-day test period, the experimental indexes and intestinal antioxidant function trends were the same as those on 14 days. The increased OFO concentration significantly increased the intestinal morphological injury score (P < 0.05). These results demonstrated that adding 4% OFO to the feed for 14 days could induce irreversible damage to the intestinal tissue structure, weaken the antioxidant function, and decrease the growth performance of zebrafish.
Description
Keywords
antioxydant, growth performance, intestinal health, oxidized fish oil
Citation
Extent
13 pages
Format
Geographic Location
Time Period
Related To
The Israeli Journal of Aquaculture - Bamidgeh
Related To (URI)
Table of Contents
Rights
Rights Holder
Local Contexts
Collections
Email libraryada-l@lists.hawaii.edu if you need this content in ADA-compliant format.